Glossary

Drugs that are used to block adrenergic receptors when the heart is beating too fast.

The fraction of the dose administered that gets into the blood.

Chemicals that are produced by living organisms and are involved in various metabolic processes.

Medications that are routinely made by biological systems. These are typically large to very large molecules including proteins, RNA or DNA. • Types of Medications • Traditional protein vaccines • RNA vaccines • Replacement protein therapeutics • Novel proteins • Monoclonal Antibodies • Vaccines • Gene therapy • Very large molecules • An entire human gene • In a viral DNA vector; the combined molecular weight can be >1 Million Daltons • Typically delivered in AAV vectors • Antibiotics • Manufactured by fermenting genetically engineered bacteria or human cells. • Enormous numbers of cells that express the desired product must be grown in enormous fermentation tanks to produce the desired medication. The medication must be purified away from all the other chemical molecules in the cells.

The manipulation of organisms or their components to produce useful products.

A bodily fluid that circulates through the heart, arteries, veins, and capillaries, carrying oxygen, nutrients, and waste products.

A slow heart rate.

The center of the nervous system, responsible for thought, emotion, and control of body functions.

An infection of the main airways of the lungs (bronchi), causing them to become irritated and inflamed. The main symptom is a cough, which may bring up yellow-grey mucus (phlegm).

Bronchospasms happen when the muscles that line your bronchi (airways in your lungs) tighten. This results in wheezing, coughing, and other symptoms.