Welcome to a NEW SERIES that pulls back the curtain on the scientific and medical breakthroughs that make n-Lorem possible. We call them miracles and without them, n-Lorem would not exist today. Every day, our patients benefit from what can only be described as miracles of science. Not the fairytale kind. Not wishes granted overnight. These miracles are earned by humans. Built over centuries by scientists whose discoveries stacked, evolved, and refined over time. They are the result of human curiosity, persistence, and an ever-deepening understanding of biology, and they’ve fundamentally changed how we see the world and treat disease.
Today’s miracle: Genomics. Coming next: iPSCs, the RNA World, and Antisense Technology. The breakthroughs that pushed possibility even further.
n-Lorem Founder and CEO, Stan Crooke, recently joined the advisory board of the CNBC Cures, an initiative bringing together families, doctors, investors and regulators with one goal in mind: helping to raise awareness of, and improve patient outcomes for, the 30 million Americans suffering from rare diseases. You can join the CNBC Cures Newsletter here.
In This Episode, We Explore:
- The Miracles of Science and what’s to come in this series
- The Miracle of Genomics and its origins
- The key observation from many centuries ago
- Curiosity and Gregory Mendel’s discovery
- The Scientific Method and incremental innovation
- X-ray crystallography helped characterize the structure of DNA
- An idea that DNA structure might be used to store genetic information
- Nature and structure of chromosomes, architecture of DNA, hybridization, replication, transcription
- Importance of the RNA World
- Translation, cloning, biotechnology, genomic sequencing, genetic diseases and medicine
- Fundamental changes in human culture
Watch on YouTube:
The host of the show is Dr. Stanley Crooke, a scientist, a physician, an entrepreneur and the father of antisense technology. Dr. Crooke is responsible for driving the development of antisense or ASO technology, an RNA-targeted technology responsible for the commercialization of three best- and first-in class medicines and more than 40 drugs in development. In 2020, Stan formed n-Lorem to use this powerful technology to develop experimental personalized ASO medicines for nano-rare patients (1 to 30 patients worldwide) for free, for life.
Listen to our next Intro to Medical Science episode

We cannot do
this alone
Together we are changing the world—
one patient at a time
We hope that you join us on this journey to discover, develop and provide individualized antisense medicines for free for life for nano-rare patients. The ultimate personalized medicine approach – for free, for life.
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