Medical Science 11

Cardiovascular System Part 4A: (The Spigot) Kidney Functions

January 18, 2023


Kidneys, the high energy consuming spigot of the cardiovascular system.

There is so much filtration around you, you may not even notice. Your water, coffee, air, gasoline, and social media feeds… all filtered. So is your blood! It’s just a part of everyday life at this point. Today’s chat is filtered around the functions of the spigot of the cardiovascular system – the Kidneys. Their main job? Kidneys filter every drop of blood in the body and remove water soluble waste. Kidneys also perform many other essential functions including helping regulate blood pressure, maintaining proper pH levels of the blood, all of which require a lot of energy and are necessary for life.

On This Episode We Discuss:

  • What are the kidneys’ main roles?
  • Glomerular filtration rate (GFR)
  • A roadmap of the liquid (filtrate) as it goes through the kidneys
  • Tiny pipes called tubules
  • Distal tubules and the loop of Henle
  • Maintaining water levels
  • Energy consumption – ATP and SGL II
  • Balancing Ion levels and pH

Watch on YouTube:

The host of the show is Dr. Stanley Crooke, a scientist, a physician, an entrepreneur and the father of antisense technology. Dr. Crooke is responsible for driving the development of antisense or ASO technology, an RNA-targeted technology responsible for the commercialization of three best- and first-in class medicines and more than 40 drugs in development. In 2020, Stan formed n-Lorem to use this powerful technology to develop experimental personalized ASO medicines for nano-rare patients (1 to 30 patients worldwide) for free, for life.


For definitions of terms, search our glossary.



Hosted by: Dr. Stan Crooke.
Videographer: Jon Magnuson of Mighty One Productions.
Producers: Kim Butler, Colin Delaney, Kira Dineen, Jon Magnuson, Andrew Serrano and Amy Williford

More from n-Lorem:

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Listen to our next Intro to Medical Science episode

Cardiovascular System Part 4B: (The Spigot) Kidney Diseases

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