I think this is critical for any organization, but especially critical for an organization attempting to create a new platform for drug discovery and developing drugs for commercial approval. We basically had two committees that made most of the key decisions in public. Research management committee (RMC) dealt with all senior decisions concerning the technology and drug discovery programs and the Development management committee (DMC) dealt with decisions concerning drug being promoted to and advancing in development. The simplicity of the process to bring a topic to one of these committees, the extensive, often energetic and sometimes contentious debates led to better decisions and the rapidity with which decisions were made led to a very nimble organization. A great bonus of transparency was the opportunity to teach drug discovery and development to many in the company.